Sfoglia per Rivista NATURE MEDICINE
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
2021-01-01 Kyriazopoulou, E.; Poulakou, G.; Milionis, H.; Metallidis, S.; Adamis, G.; Tsiakos, K.; Fragkou, A.; Rapti, A.; Damoulari, C.; Fantoni, M.; Kalomenidis, I.; Chrysos, G.; Angheben, A.; Kainis, I.; Alexiou, Z.; Castelli, F.; Serino, F. S.; Tsilika, M.; Bakakos, P.; Nicastri, E.; Tzavara, V.; Kostis, E.; Dagna, L.; Koufargyris, P.; Dimakou, K.; Savvanis, S.; Tzatzagou, G.; Chini, M.; Cavalli, Giulio.; Bassetti, M.; Katrini, K.; Kotsis, V.; Tsoukalas, G.; Selmi, C.; Bliziotis, I.; Samarkos, M.; Doumas, M.; Ktena, S.; Masgala, A.; Papanikolaou, I.; Kosmidou, M.; Myrodia, D. -M.; Argyraki, A.; Cardellino, C. S.; Koliakou, K.; Katsigianni, E. -I.; Rapti, V.; Giannitsioti, E.; Cingolani, A.; Micha, S.; Akinosoglou, K.; Liatsis-Douvitsas, O.; Symbardi, S.; Gatselis, N.; Mouktaroudi, M.; Ippolito, G.; Florou, E.; Kotsaki, A.; Netea, M. G.; Eugen-Olsen, J.; Kyprianou, M.; Panagopoulos, P.; Dalekos, G. N.; Giamarellos-Bourboulis, E. J.
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
2012-01-01 Provasi, E; Genovese, P; Lombardo, ANGELO LEONE; Magnani, Z; Liu Pei, Q; Reik, A; Chu, V; Paschon, D. E.; Zhang, L; Kuball, J; Camisa, B; Bondanza, Attilio; Casorati, G; Ponzoni, Maurilio; Ciceri, Fabio; Bordignon, Claudio; Greenberg, P. D.; Holmes, Mc; Gregory, Pd; Naldini, Luigi; Bonini, MARIA CHIARA
Endogenous microRNA Regulation Suppresses Transgene Expression in Hematopoietic Lineages and Enables Stable Gene Transfer
2006-01-01 D, Brown B.; Venneri M., A.; Zingale, A; Nulll, nullSergi Sergi; Naldini, Luigi
Ensuring a future for gene therapy for rare diseases
2022-01-01 Aiuti, A.; Pasinelli, F.; Naldini, L.
Epithelial calcineurin controls microbiota-dependent intestinal tumor development
2016-01-01 Peuker, K; Muff, S; Wang, J; Künzel, S; Bosse, E; Zeissig, Y; Luzzi, G; Basic, M; Strigli, A; Ulbricht, A; Kaser, A; Arlt, A; Chavakis, T; van den Brink, Gr; Schafmayer, C; Egberts, J. H.; Becker, T; Bianchi, MARCO EMILIO; Bleich, A; Röcken, C; Hampe, J; Schreiber, S; Baines, Jf; Blumberg, Rs; Zeissig, S.
Generation of primary antigen-specific human T- and B-cell responses in immunocompetent SCID-hu mice
2000-01-01 Carballido, J. M.; Namikawa, R.; CARBALLIDO PERIG, N.; Antonenko, S.; Roncarolo, MARIA GRAZIA; DE VRIES, J. E.
Genome editing: a tool for research and therapy: Targeted genome editing hits the clinic
2014-01-01 Lombardo, ANGELO LEONE; Naldini, Luigi
Has SARS-CoV-2 reached peak fitness?
2021-01-01 Burioni, R.; Topol, E. J.
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement
2002-01-01 Aiuti, Alessandro; Vai, S; Mortellaro, A; Casorati, G; Ficara, F; Andolfi, G; Ferrari, Giuliana; Tabucchi, A; Carlucci, F; Ochs, Hd; Notarangelo, Ld; Roncarolo, MARIA GRAZIA; Bordignon, Claudio
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation
2019-01-01 Toffalori, C.; Zito, L.; Gambacorta, V.; Riba, M.; Oliveira, G.; Bucci, G.; Barcella, M.; Spinelli, O.; Greco, R.; Crucitti, L.; Cieri, N.; Noviello, M.; Manfredi, F.; Montaldo, E.; Ostuni, R.; Naldini, M. M.; Gentner, B.; Waterhouse, M.; Zeiser, R.; Finke, J.; Hanoun, M.; Beelen, D. W.; Gojo, I.; Luznik, L.; Onozawa, M.; Teshima, T.; Devillier, R.; Blaise, D.; Halkes, C. J. M.; Griffioen, M.; Carrabba, M. G.; Bernardi, M.; Peccatori, J.; Barlassina, C.; Stupka, E.; Lazarevic, D.; Tonon, G.; Rambaldi, A.; Cittaro, D.; Bonini, C.; Fleischhauer, K.; Ciceri, F.; Vago, L.
In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice
2001-01-01 Consiglio, A.; Quattrini, A; Martino, S.; Bensadoun, J. C.; Dolcetta, D.; Trojani, A.; Benaglia, G.; Marchesini, S.; Cestari, V.; Oliviero, A; Bordignon, Claudio; Naldini, Luigi
Induction of a non-encephalitogenic T2 helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial.
2000-01-01 Kappos, L; Comi, G; Panitch, H; Oger, J; Antel, J; Conlon, P; Steinman, L; the APL in Relapsing MS Study Group, With; Filippi, Massimo
Inserting optimism into gene therapy
2006-01-01 Naldini, Luigi
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia
2019-01-01 Marktel, Sarah; Scaramuzza, Samantha; Cicalese, Maria Pia; Giglio, Fabio; Galimberti, Stefania; Lidonnici, Maria Rosa; Calbi, Valeria; Assanelli, Andrea; Bernardo, Maria Ester; Rossi, Claudia; Calabria, Andrea; Milani, Raffaella; Gattillo, Salvatore; Benedicenti, Fabrizio; Spinozzi, Giulio; Aprile, Annamaria; Bergami, Alessandra; Casiraghi, Miriam; Consiglieri, Giulia; Masera, Nicoletta; D’Angelo, Emanuela; Mirra, Nadia; Origa, Raffaella; Tartaglione, Immacolata; Perrotta, Silverio; Winter, Robert; Coppola, Milena; Viarengo, Gianluca; Santoleri, Luca; Graziadei, Giovanna; Gabaldo, Michela; Valsecchi, Maria Grazia; Montini, Eugenio; Naldini, Luigi; Cappellini, Maria Domenica; Ciceri, Fabio; Aiuti, Alessandro; Ferrari, Giuliana
The molecular landscape of glioma in patients with Neurofibromatosis 1
2019-01-01 D'Angelo, F.; Ceccarelli, M.; Tala, ; Garofano, L.; Zhang, J.; Frattini, V.; Caruso, F. P.; Lewis, G.; Alfaro, K. D.; Bauchet, L.; Berzero, G.; Cachia, D.; Cangiano, M.; Capelle, L.; de Groot, J.; Dimeco, F.; Ducray, F.; Farah, W.; Finocchiaro, G.; Goutagny, S.; Kamiya-Matsuoka, C.; Lavarino, C.; Loiseau, H.; Lorgis, V.; Marras, C. E.; Mccutcheon, I.; Nam, D. -H.; Ronchi, S.; Saletti, V.; Seizeur, R.; Slopis, J.; Sunol, M.; Vandenbos, F.; Varlet, P.; Vidaud, D.; Watts, C.; Tabar, V.; Reuss, D. E.; Kim, S. -K.; Meyronet, D.; Mokhtari, K.; Salvador, H.; Bhat, K. P.; Eoli, M.; Sanson, M.; Lasorella, A.; Iavarone, A.
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
2018-01-01 Norelli, Margherita; Camisa, Barbara; Barbiera, Giulia; Falcone, Laura; Purevdorj, Ayurzana; Genua, Marco; Sanvito, Francesca; Ponzoni, Maurilio; Doglioni, Claudio; Cristofori, Patrizia; Traversari, Catia; Bordignon, Claudio; Ciceri, Fabio; Ostuni, Renato; Bonini, Chiara; Casucci, Monica; Bondanza, Attilio
Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study
2023-01-01 Genchi, Angela; Brambilla, Elena; Sangalli, Francesca; Radaelli, Marta; Bacigaluppi, Marco; Furlan, Roberto; Andolfo, Annapaola; Drago, Denise; Magagnotti, Cinzia; Scotti, Giulia Maria; Greco, Raffaella; Vezzulli, Paolo; Ottoboni, Linda; Bonopane, Marco; Capilupo, Daniela; Ruffini, Francesca; Belotti, Daniela; Cabiati, Benedetta; Cesana, Stefania; Matera, Giada; Leocani, Letizia; Martinelli, Vittorio; Moiola, Lucia; Vago, Luca; Panina-Bordignon, Paola; Falini, Andrea; Ciceri, Fabio; Uglietti, Anna; Sormani, Maria Pia; Comi, Giancarlo; Battaglia, Mario Alberto; Rocca, Maria A; Storelli, Loredana; Pagani, Elisabetta; Gaipa, Giuseppe; Martino, Gianvito
Platelet GPIb alpha is a mediator and potential interventional target for NASH and subsequent liver cancer
2019-01-01 Malehmir, M; Pfister, D; Gallage, S; Szydlowska, M; Inverso, D; Kotsiliti, E; Leone, V; Peiseler, M; Surewaard, Bgj; Rath, D; Ali, A; Wolf, Mj; Drescher, H; Healy, Me; Dauch, D; Kroy, D; Krenkel, O; Kohlhepp, M; Engleitner, T; Olkus, A; Sijmonsma, T; Volz, J; Deppermann, C; Stegner, D; Helbling, P; Nombela-Arrieta, C; Rafiei, A; Hinterleitner, M; Rall, M; Baku, F; Borst, O; Wilson, Cl; Leslie, J; O'Connor, T; Weston, Cj; Adams, Dh; Sheriff, L; Teijeiro, A; Prinz, M; Bogeska, R; Anstee, N; Bongers, Mn; Notohamiprodjo, M; Geisler, T; Withers, Dj; Ware, J; Mann, Da; Augustin, Hg; Vegiopoulos, A; Milsom, Md; Rose, Aj; Lalor, Pf; Llovet, Jm; Pinyol, R; Tacke, F; Rad, R; Matter, M; Djouder, N; Kubes, P; Knolle, Pa; Unger, K; Zender, L; Nieswandt, B; Gawaz, M; Weber, A; Heikenwalder, M
Platelets mediate cytotoxic T lymphocyte-induced liver damage
2005-01-01 Iannacone, M; Sitia, G; Isogawa, M; Marchese, P; Castro, Mg; Lowenstein, Pr; Chisari, Fv; Ruggeri, Zm; Guidotti, Luca
Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers
2014-01-01 Cottini, F; Hideshima, T; Xu, C; Sattler, M; Dori, M; Agnelli, L; ten Hacken, E; Bertilaccio, Mt; Antonini, E; Neri, A; Ponzoni, Maurilio; Marcatti, M; Richardson, Pg; Carrasco, R; Kimmelman, Ac; Wong, Kk; Caligaris Cappio, F; Blandino, G; Kuehl, Wm; Anderson, Kc; Tonon, G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial | 1-gen-2021 | Kyriazopoulou, E.; Poulakou, G.; Milionis, H.; Metallidis, S.; Adamis, G.; Tsiakos, K.; Fragkou, A.; Rapti, A.; Damoulari, C.; Fantoni, M.; Kalomenidis, I.; Chrysos, G.; Angheben, A.; Kainis, I.; Alexiou, Z.; Castelli, F.; Serino, F. S.; Tsilika, M.; Bakakos, P.; Nicastri, E.; Tzavara, V.; Kostis, E.; Dagna, L.; Koufargyris, P.; Dimakou, K.; Savvanis, S.; Tzatzagou, G.; Chini, M.; Cavalli, Giulio.; Bassetti, M.; Katrini, K.; Kotsis, V.; Tsoukalas, G.; Selmi, C.; Bliziotis, I.; Samarkos, M.; Doumas, M.; Ktena, S.; Masgala, A.; Papanikolaou, I.; Kosmidou, M.; Myrodia, D. -M.; Argyraki, A.; Cardellino, C. S.; Koliakou, K.; Katsigianni, E. -I.; Rapti, V.; Giannitsioti, E.; Cingolani, A.; Micha, S.; Akinosoglou, K.; Liatsis-Douvitsas, O.; Symbardi, S.; Gatselis, N.; Mouktaroudi, M.; Ippolito, G.; Florou, E.; Kotsaki, A.; Netea, M. G.; Eugen-Olsen, J.; Kyprianou, M.; Panagopoulos, P.; Dalekos, G. N.; Giamarellos-Bourboulis, E. J. | |
| Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer | 1-gen-2012 | Provasi, E; Genovese, P; Lombardo, ANGELO LEONE; Magnani, Z; Liu Pei, Q; Reik, A; Chu, V; Paschon, D. E.; Zhang, L; Kuball, J; Camisa, B; Bondanza, Attilio; Casorati, G; Ponzoni, Maurilio; Ciceri, Fabio; Bordignon, Claudio; Greenberg, P. D.; Holmes, Mc; Gregory, Pd; Naldini, Luigi; Bonini, MARIA CHIARA | |
| Endogenous microRNA Regulation Suppresses Transgene Expression in Hematopoietic Lineages and Enables Stable Gene Transfer | 1-gen-2006 | D, Brown B.; Venneri M., A.; Zingale, A; Nulll, nullSergi Sergi; Naldini, Luigi | |
| Ensuring a future for gene therapy for rare diseases | 1-gen-2022 | Aiuti, A.; Pasinelli, F.; Naldini, L. | |
| Epithelial calcineurin controls microbiota-dependent intestinal tumor development | 1-gen-2016 | Peuker, K; Muff, S; Wang, J; Künzel, S; Bosse, E; Zeissig, Y; Luzzi, G; Basic, M; Strigli, A; Ulbricht, A; Kaser, A; Arlt, A; Chavakis, T; van den Brink, Gr; Schafmayer, C; Egberts, J. H.; Becker, T; Bianchi, MARCO EMILIO; Bleich, A; Röcken, C; Hampe, J; Schreiber, S; Baines, Jf; Blumberg, Rs; Zeissig, S. | |
| Generation of primary antigen-specific human T- and B-cell responses in immunocompetent SCID-hu mice | 1-gen-2000 | Carballido, J. M.; Namikawa, R.; CARBALLIDO PERIG, N.; Antonenko, S.; Roncarolo, MARIA GRAZIA; DE VRIES, J. E. | |
| Genome editing: a tool for research and therapy: Targeted genome editing hits the clinic | 1-gen-2014 | Lombardo, ANGELO LEONE; Naldini, Luigi | |
| Has SARS-CoV-2 reached peak fitness? | 1-gen-2021 | Burioni, R.; Topol, E. J. | |
| Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement | 1-gen-2002 | Aiuti, Alessandro; Vai, S; Mortellaro, A; Casorati, G; Ficara, F; Andolfi, G; Ferrari, Giuliana; Tabucchi, A; Carlucci, F; Ochs, Hd; Notarangelo, Ld; Roncarolo, MARIA GRAZIA; Bordignon, Claudio | |
| Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation | 1-gen-2019 | Toffalori, C.; Zito, L.; Gambacorta, V.; Riba, M.; Oliveira, G.; Bucci, G.; Barcella, M.; Spinelli, O.; Greco, R.; Crucitti, L.; Cieri, N.; Noviello, M.; Manfredi, F.; Montaldo, E.; Ostuni, R.; Naldini, M. M.; Gentner, B.; Waterhouse, M.; Zeiser, R.; Finke, J.; Hanoun, M.; Beelen, D. W.; Gojo, I.; Luznik, L.; Onozawa, M.; Teshima, T.; Devillier, R.; Blaise, D.; Halkes, C. J. M.; Griffioen, M.; Carrabba, M. G.; Bernardi, M.; Peccatori, J.; Barlassina, C.; Stupka, E.; Lazarevic, D.; Tonon, G.; Rambaldi, A.; Cittaro, D.; Bonini, C.; Fleischhauer, K.; Ciceri, F.; Vago, L. | |
| In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice | 1-gen-2001 | Consiglio, A.; Quattrini, A; Martino, S.; Bensadoun, J. C.; Dolcetta, D.; Trojani, A.; Benaglia, G.; Marchesini, S.; Cestari, V.; Oliviero, A; Bordignon, Claudio; Naldini, Luigi | |
| Induction of a non-encephalitogenic T2 helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial. | 1-gen-2000 | Kappos, L; Comi, G; Panitch, H; Oger, J; Antel, J; Conlon, P; Steinman, L; the APL in Relapsing MS Study Group, With; Filippi, Massimo | |
| Inserting optimism into gene therapy | 1-gen-2006 | Naldini, Luigi | |
| Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia | 1-gen-2019 | Marktel, Sarah; Scaramuzza, Samantha; Cicalese, Maria Pia; Giglio, Fabio; Galimberti, Stefania; Lidonnici, Maria Rosa; Calbi, Valeria; Assanelli, Andrea; Bernardo, Maria Ester; Rossi, Claudia; Calabria, Andrea; Milani, Raffaella; Gattillo, Salvatore; Benedicenti, Fabrizio; Spinozzi, Giulio; Aprile, Annamaria; Bergami, Alessandra; Casiraghi, Miriam; Consiglieri, Giulia; Masera, Nicoletta; D’Angelo, Emanuela; Mirra, Nadia; Origa, Raffaella; Tartaglione, Immacolata; Perrotta, Silverio; Winter, Robert; Coppola, Milena; Viarengo, Gianluca; Santoleri, Luca; Graziadei, Giovanna; Gabaldo, Michela; Valsecchi, Maria Grazia; Montini, Eugenio; Naldini, Luigi; Cappellini, Maria Domenica; Ciceri, Fabio; Aiuti, Alessandro; Ferrari, Giuliana | |
| The molecular landscape of glioma in patients with Neurofibromatosis 1 | 1-gen-2019 | D'Angelo, F.; Ceccarelli, M.; Tala, ; Garofano, L.; Zhang, J.; Frattini, V.; Caruso, F. P.; Lewis, G.; Alfaro, K. D.; Bauchet, L.; Berzero, G.; Cachia, D.; Cangiano, M.; Capelle, L.; de Groot, J.; Dimeco, F.; Ducray, F.; Farah, W.; Finocchiaro, G.; Goutagny, S.; Kamiya-Matsuoka, C.; Lavarino, C.; Loiseau, H.; Lorgis, V.; Marras, C. E.; Mccutcheon, I.; Nam, D. -H.; Ronchi, S.; Saletti, V.; Seizeur, R.; Slopis, J.; Sunol, M.; Vandenbos, F.; Varlet, P.; Vidaud, D.; Watts, C.; Tabar, V.; Reuss, D. E.; Kim, S. -K.; Meyronet, D.; Mokhtari, K.; Salvador, H.; Bhat, K. P.; Eoli, M.; Sanson, M.; Lasorella, A.; Iavarone, A. | |
| Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells | 1-gen-2018 | Norelli, Margherita; Camisa, Barbara; Barbiera, Giulia; Falcone, Laura; Purevdorj, Ayurzana; Genua, Marco; Sanvito, Francesca; Ponzoni, Maurilio; Doglioni, Claudio; Cristofori, Patrizia; Traversari, Catia; Bordignon, Claudio; Ciceri, Fabio; Ostuni, Renato; Bonini, Chiara; Casucci, Monica; Bondanza, Attilio | |
| Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study | 1-gen-2023 | Genchi, Angela; Brambilla, Elena; Sangalli, Francesca; Radaelli, Marta; Bacigaluppi, Marco; Furlan, Roberto; Andolfo, Annapaola; Drago, Denise; Magagnotti, Cinzia; Scotti, Giulia Maria; Greco, Raffaella; Vezzulli, Paolo; Ottoboni, Linda; Bonopane, Marco; Capilupo, Daniela; Ruffini, Francesca; Belotti, Daniela; Cabiati, Benedetta; Cesana, Stefania; Matera, Giada; Leocani, Letizia; Martinelli, Vittorio; Moiola, Lucia; Vago, Luca; Panina-Bordignon, Paola; Falini, Andrea; Ciceri, Fabio; Uglietti, Anna; Sormani, Maria Pia; Comi, Giancarlo; Battaglia, Mario Alberto; Rocca, Maria A; Storelli, Loredana; Pagani, Elisabetta; Gaipa, Giuseppe; Martino, Gianvito | |
| Platelet GPIb alpha is a mediator and potential interventional target for NASH and subsequent liver cancer | 1-gen-2019 | Malehmir, M; Pfister, D; Gallage, S; Szydlowska, M; Inverso, D; Kotsiliti, E; Leone, V; Peiseler, M; Surewaard, Bgj; Rath, D; Ali, A; Wolf, Mj; Drescher, H; Healy, Me; Dauch, D; Kroy, D; Krenkel, O; Kohlhepp, M; Engleitner, T; Olkus, A; Sijmonsma, T; Volz, J; Deppermann, C; Stegner, D; Helbling, P; Nombela-Arrieta, C; Rafiei, A; Hinterleitner, M; Rall, M; Baku, F; Borst, O; Wilson, Cl; Leslie, J; O'Connor, T; Weston, Cj; Adams, Dh; Sheriff, L; Teijeiro, A; Prinz, M; Bogeska, R; Anstee, N; Bongers, Mn; Notohamiprodjo, M; Geisler, T; Withers, Dj; Ware, J; Mann, Da; Augustin, Hg; Vegiopoulos, A; Milsom, Md; Rose, Aj; Lalor, Pf; Llovet, Jm; Pinyol, R; Tacke, F; Rad, R; Matter, M; Djouder, N; Kubes, P; Knolle, Pa; Unger, K; Zender, L; Nieswandt, B; Gawaz, M; Weber, A; Heikenwalder, M | |
| Platelets mediate cytotoxic T lymphocyte-induced liver damage | 1-gen-2005 | Iannacone, M; Sitia, G; Isogawa, M; Marchese, P; Castro, Mg; Lowenstein, Pr; Chisari, Fv; Ruggeri, Zm; Guidotti, Luca | |
| Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers | 1-gen-2014 | Cottini, F; Hideshima, T; Xu, C; Sattler, M; Dori, M; Agnelli, L; ten Hacken, E; Bertilaccio, Mt; Antonini, E; Neri, A; Ponzoni, Maurilio; Marcatti, M; Richardson, Pg; Carrasco, R; Kimmelman, Ac; Wong, Kk; Caligaris Cappio, F; Blandino, G; Kuehl, Wm; Anderson, Kc; Tonon, G. |
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